SCIENCE
KNOWHEN® Clinical studies were performed in Manhattan Fertility Center by Dr. Hugh Melnik. Dr. Melnick has been treating infertile couples since 1976, and is considered a pioneer in the field of outpatient in vitro fertilization. Dr. Melnick has lectured on topics related to infertility and reproductive endocrinology. In 1983 he founded Advanced Fertility Services, the first private, freestanding in vitro fertilization center in the greater New York area and has been its director ever since. Dr. Melnick’s studies found a close correlation between actual ovulation as determined by sonographic examination of the ovaries and the presence of a ferning pattern in saliva as determined by the KNOWHEN® Ovulation Predictor System. In addition, two women in the studies who had been trying to get pregnant for years using different methods conceived at the first attempt, using the KNOWHEN® saliva fertility monitor.